Pure Wood Cellulose Is Used To Create Microcrystalline Cellulose
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| Microcrystalline Cellulose |
Microcrystalline
Cellulose (MCC) is a
commonly used excipient in the pharmaceutical, food, and cosmetic industries.
It is a refined form of wood pulp that has been processed into a fine, white
powder. MCC is primarily used as a binder, disintegrant, and filler in various
formulations. In this article, we will discuss how MCC works and its role in
various applications.
MCC works by its unique physical and chemical properties. It
has a high surface area and is porous, which allows it to absorb water and
other liquids. When MCC is added to a formulation, it can swell and form a
gel-like substance, which helps to improve the texture and flow properties of
the product.
As a binder, Microcrystalline
Cellulose
helps to hold together the active ingredients in a tablet or capsule. It forms
a strong, cohesive bond that prevents the tablet or capsule from falling apart
during storage or transport. MCC is particularly useful for tablets that
contain low-dose or potent drugs, as it can help to ensure that the drug is
evenly distributed throughout the tablet.
As a disintegrant, MCC helps to break down tablets or
capsules in the gastrointestinal tract. When the tablet or capsule reaches the
stomach, the MCC absorbs water and swells, causing the tablet or capsule to
break apart. This process helps to release the active ingredients, allowing
them to be absorbed into the bloodstream.
As a filler, Microcrystalline
Cellulose can be
used to increase the volume of a tablet or capsule. This is particularly useful
for low-dose formulations, where the amount of active ingredient is too small
to fill the entire capsule or tablet. By adding MCC as a filler, the tablet or
capsule can be made to the desired size.
MCC is also used as a fat replacer in low-fat and
reduced-calorie foods. It can mimic the texture and mouthfeel of fat, while
providing fewer calories. This makes it an attractive option for manufacturers
looking to reduce the calorie content of their products without sacrificing
taste or texture.
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