Gastroparesis Treatment Helps To Keep Gastroparesis Disease under Control
Gastroparesis Treatment |
Gastroparesis impairs the
stomach's spontaneous muscle movement (motility). Gastroparesis can disrupt
normal digestion and result in nausea, vomiting, and abdominal pain. It has an
impact on blood sugar levels and nutrition. Medical treatment and dietary changes
can help control the condition. To treat gastroparesis, medications such as
domperidone, erythromycin, anti-emetics, and others are used. Clinical trials
have yielded promising results for drug candidates being developed and
investigated for the treatment of gastroparesis. As a result, regulatory
agencies such as the United States Food and Drug Administration (FDA) are
bestowing designations on drug candidates.
As the prevalence of
gastroparesis rises, so will the demand for novel treatment products. According
to the National Institute of Diabetes and Digestive and Kidney Diseases, in
January 2018, approximately 10 men and 40 women out of 100,000 people in the
United States had gastroparesis. The novel treatment significantly improved the
symptoms of gastroparesis patients (diabetic gastroparesis and idiopathic
gastroparesis). The prokinetic ghrelin agonist relamorelin, the prokinetic
serotonergic agents velusetrag and prucalopride, the anti-emetic aprepitant,
and per-endoscopic pyloric myotomy procedures are all being studied for
gastroparesis. In November 2016, for example, Emory University School of
Medicine researchers demonstrated positive short-term outcomes for gastric per
oral endoscopic pyloromyotomy, or G-POEM, a minimally invasive procedure.
The side effects of Gastroparesis
Treatment will vary depending on the medication, dose, and the
patient's other medical conditions. Some of the most common side effects
associated with prokinetics are fatigue, drowsiness, sedation, anxiety, and
restlessness.s
Identifying and treating the
underlying condition is the first step in treating gastroparesis. If diabetes
is the cause of your gastroparesis, your doctor can help you control it. The
most important goal in the treatment of gastroparesis is to maintain adequate
nutrition. Many people can control their gastroparesis by making dietary
changes. Your doctor may refer you to a dietitian who can help you find foods
that are easier to digest.
A surgically implanted device
delivers electrical stimulation to the stomach muscles to help them move food
more efficiently. The device appears to be most useful for people with diabetic
gastroparesis. The FDA has granted the device a compassionate use exemption for
those who are unable to control their gastroparesis symptoms with diet changes
or medications. Larger studies, however, are required.
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